Zuva reWorld Diabetes Day ndiyo hurongwa hwekutanga hwekuzivisa pasi rose hunotarisa nezvechirwere cheshuga uye hunoitwa musi wa14 Mbudzi gore rega rega.
Yakatungamirirwa neInternational Diabetes Federation (IDF), zuva rega rega reWorld Diabetes Day rinotarisa dingindira rine chekuita nechirwere cheshuga;Type-2 chirwere cheshuga chinonyanya kudzivirirwa uye chinorapika chisingatapuriranwe chiri kukurumidza kuwedzera muhuwandu pasi rose.Type 1 chirwere cheshuga hachidziviriki asi chinogona kurapwa nemajekiseni e insulin.Misoro yakakurukurwa yaisanganisira chirwere cheshuga nekodzero dzevanhu, chirwere cheshuga nemararamiro, chirwere cheshuga nekufutisa, chirwere cheshuga kune vanotambura nevanotambura, uye chirwere cheshuga muvana nevachiri kuyaruka.
Chii chinonzi chirwere cheshuga?
Chirwere cheshuga chirwere chisingaperi chinoitika kana pancreas ikasaburitsa insulin yakakwana kana kuti muviri usingakwanise kushandisa insulin yaunoburitsa.Insulin ihomoni inodzora shuga yeropa.Hyperglycemia, kana kukwidziridzwa kweshuga yeropa, mhedzisiro yechirwere cheshuga chisingadzoreki, icho nekufamba kwenguva chinogona kukanganisa zvirongwa zvakawanda mumuviri, kunyanya tsinga netsinga.
Kuongororwa kwakanangana neshuga kunonyanya kuongororwa shuga yeropa, kusanganisira kutsanya kweglucose yeropa, glucose tolerance test (OGTT), uye glycosylated hemoglobin.Kunyangwe kuongororwa kweglucose yeropa kuchishandiswa zvakanyanya, panogona kunge paine zvimwe zvisingabatsiri.Semuenzaniso, inogona kungotarisa huwandu hweglucose yeropa mumuviri, uye cheki imwechete yekutsanya yeropa glucose inogona kuita kuti imwe chirwere cheshuga chishaikwe.yakakwirira kana yakajairika.Sezvo hyperglycemia inokonzerwa nekukanganiswa kwe insulin secretion kana mhedzisiro yayo yehupenyu, kana zvese zviri zviviri, pane kudikanwa kwekuwedzera kunzwisisika kwezviratidzo zvekudzivirira kwe insulin mukuita kwekiriniki.
Nhanganyaya kune insulin uye C-peptide:
Insulinine 51 amino acids inoumbwa nemacheni maviri epeptide, A uye B, akabatanidzwa pamwechete nema bond maviri e disulfide.Inotorwa kubva ku-β-pancreatic masero.Basa rayo guru nderokusimudzira kutendeuka kweglucose uye kugadzirwa kweglycogen, uye inhibit gluconeogenesis.Nokudaro kuchengetedza kugadzikana kweshuga yeropa.
C-peptideinovanzwa nepancreatic β-cells uye ine yakajairwa precursor, proinsulin, ine insulin.Proinsulin yakakamurwa kuita 1 molecule ye insulin uye 1 molecule yeC-peptide, saka molar mass yeC-peptide inopindirana ne insulin yayo, uye kuyera C-peptide kuyera zviri mukati insulin.Panguva imwecheteyo, haina kuvharwa nechiropa se insulin mu metabolic process, uye hafu yehupenyu hwayo hwakareba kupfuura iyo insulin, saka iyo C-peptide iri muropa reperipheral yakagadzikana kupfuura insulin, uye haina. yakakanganiswa ne exogenous insulin,saka inogona kuratidza zvirinani Pancreatic β-cell basa.
Ndezvipi zviratidzo zvekliniki?
Insulin uye C-peptide zviratidzo zvakakosha zvekuona insulin.Kuburikidza nemiedzo miviri iyi, varwere vanogona kuziva kana vari kushaya insulin zvachose kana kushaya insulin, vangave vari Type 1 chirwere cheshuga kana Type 2 chirwere cheshuga.
Type 1 chirwere cheshuga, yaimbozivikanwa sechirwere cheshuga chinotsamira pa insulin, chinokonzeresa10%yehuwandu hwehuwandu hwevarwere vane chirwere cheshuga uye inowanzoitika muvana nevechiri kuyaruka.
Chikonzero ndechekuti pancreatic islet B masero anoparadzwa nesero-mediated autoimmunity uye haakwanise kugadzira uye kuburitsa insulin yega.Panogona kuva nemhando dzakasiyana-siyana dzeautoantibodies mu seramu pakutanga kwechirwere.Kana chirwere cheshuga 1 chikaitika, zviratidzo zvechirwere cheshuga zvinonyanya kuoneka, uye ketosis inowanzoitika, ndiko kuti, pane katsika ketosis, uye inoda kuvimba ne insulin yekunze kuti irarame.Kana iyo insulin yakamira kurapwa, ichave inoisa hupenyu panjodzi.Mushure mekugamuchira kurapwa kwe insulin, basa repancreatic islet B masero rinovandudza, nhamba yeB masero inowedzerawo, zviratidzo zvekiriniki zvinovandudza, uye chiyero che insulin chinogona kuderedzwa.Iyi ndiyo inonzi honeymoon period, inogona kugara kwemwedzi yakati wandei.Mushure mezvo, sezvo chirwere ichi chichienderera mberi,zvichiri kudikanwa kuvimba nerubatsiro rwekunze kune insulin kudzora mazinga eshuga yeropa uye kudzivirira ketone kugadzirwa kwemuviri.
Type 2 chirwere cheshuga, yaimbozivikanwa sechirwere cheshuga chisingaiti-insulini, chinoverengera90%yehuwandu hwehuwandu hwevarwere vane chirwere cheshuga, uye vazhinji vavo vanoonekwa mushure memakore makumi matatu nemashanu.
Kutanga kunononoka uye kunonyengera.Masero eIslet anoburitsa yakawanda kana shoma insulin, kana yakajairika, uye iyo yepamusoro yekuvanzika inochinja gare gare.Inenge 60% yevarwere vane Type 2 chirwere cheshuga vakafuta kana kufuta.Kudya kwenguva refu, kudya kwekoriori yakawanda, kuwedzera uremu zvishoma nezvishoma, uye kunyange kufutisa.Kufutisa kunotungamirira ku insulin kuramba, yakakwira shuga yeropa, uye hapana hunhu huri pachena hwekuita ketosis.Vazhinji varwere vanogona kugadzikana kudzora shuga yeropa mushure mekudzora kwekudya uye nemuromo hypoglycemic zvinodhaka;zvisinei, vamwe varwere, kunyanya vakafutisa varwere, vanoda exogenous insulin kudzora shuga muropa.Chirwere cheshuga cherudzi rwechipiri chine nhaka yemhuri zviri pachena.
Nzira yekudzivirira sei chirwere cheshuga?
Zvinofungidzirwa kuti vanhu vakuru vane mamiriyoni e422 pasi rose vaiva nechirwere cheshuga muna 2014, kubva pamamiriyoni 108 muna 1980. Uyezve, kuwanda kwepasi rose kwechirwere cheshuga kwakapetwa kaviri kubva muna 1980, kubva pa 4.7% kusvika ku8.5% yevanhu vakuru.Chirwere cheshuga chinouraya vanhu 3.4 miriyoni gore rega rega uye, chikasarapwa nemazvo, chinogona kukonzera kuremara kwemuviri kusanganisira upofu.Izvi zvinoratidza kuti zvinhu zvine chekuita nenjodzi senge kuwandisa kana kufutisa zviri kuwedzerawo.Kuwanda kwechirwere cheshuga kwakawedzera nekukurumidza munyika dzine mari yakaderera uye yepakati pane munyika dzine mari yakawanda mumakore gumi apfuura.Nhau dzakanaka ndedzekuti kuburikidza nekurapa uye kudzora maitiro, vanhu vane chirwere cheshuga vanogona kurarama hupenyu hwakajairika uye hupenyu sevanhu vane hutano.
Saka, ngatitaurei nemi nzira shoma dzekudzivirira chirwere cheshuga:
1. Kusimbisa muviri: Kugara uchirovedza muviri ndiyo imwe yenzira dzakanakisisa dzekudzivirira kana kudzora rudzi rwechipiri rwechirwere cheshuga.Kutaura idi, zvose zviri zviviri kusaita muviri uye kusashanda kwenguva refu kungawedzera ngozi yechirwere cheshuga.Kugara uchirovedza muviri kunogona kuvandudza kugona kwetsandanyama kushandisa insulin uye kunwisa shuga, uye kunogonawo kuderedza kumanikidzwa kwemamwe masero anogadzira insulin.Kuita maekisesaizi kune imwe bhenefiti, iyo ndeyokuti inogona kukubatsira kuderedza uremu.Chero bedzi uchigona kupedza mazuva mashanu pavhiki uchirovedza muviri kwemaminitsi makumi matatu nguva imwe neimwe, zvichabatsira zvikuru kuvandudza BP uye cholesterol.Kuita maekisesaizi ndiyo nzira inoshanda zvikuru yekurwisa chirwere cheshuga.
2. Kudya kwakanaka: Kudya kunovaka muviri kwakakosha kudzivirira kana kudzora chirwere cheshuga.Pakusarudza zvinwiwa, unofanira kusarudza mvura yakachena, zvinwiwa zvisina shuga, kana kofi isina shuga, uye ugare kure nezvinwiwa zvine shuga.Vana nevakuru vanogara vachinwa zvinwiwa zvine shuga vanowanzove vakafuta.Uyezve, zvinwiwa zvine shuga zvinogona kuita kuti insulin isarambe.Mukutaura kwekudya kwemafuta, unofanira kudzivisa "mafuta akaipa" uye sarudza "mafuta akanaka".Kudya mafuta emiriwo uye nut mafuta kunogona kuwedzera kugamuchirwa kweglucose ne insulin receptors mumisumbu yevanhu uye kubatsira kudzivirira rudzi rwechipiri chirwere cheshuga.Deredza kudyiwa kwemakabhohaidhiretsi akagayiwa, akadai sechingwa chichena nemupunga, sezvo achigona kukwidza shuga yemuropa ne insulin.Chekupedzisira, rega kudya nyama tsvuku uye edza kudya zvine hutano mapuroteni, sehuku kana hove.
3. Kudzora uremu: Kufutisa ndicho chikonzero chikuru chechirwere cheshuga cherudzi rwechipiri.Vanhu vakafutisa vane mukana wakapetwa makumi maviri kusvika makumi mana wekuwana chirwere cheshuga kupfuura vanhuwo zvavo vane huremu.Chirwere cheshuga chinogona kudzivirirwa zvachose uye kudzorwa kuburikidza nekudya kwakadzikama, kune hutano uye kurovedza muviri nguva dzose.Maererano ne "Diabetes Prevention Programme (DPP)" kudzidza muUnited States, zvichienzaniswa nevarwere vakagamuchira kurapwa kwepa placebo, varwere vakawana makore matatu ekupindira kwemararamiro (ILS) vane 58% kuderedza dambudziko rekuita chirwere cheshuga.Zvakakosha kuziva kuti vadzidzi vakawanawo kuti, paavhareji, kirogiramu yega yega yakarasika inoderedza njodzi yekuva nechirwere cheshuga ne16%, uye nhamba idzi dzinofanira kushanda sekukurudzira iwe kuti uchengetedze huremu hune hutano.
4. Kugara uchiongororwa utano: Kugara uchiongororwa hutano uye kuongororwa kwechirwere cheshuga kunogona kupa ruzivo rwakakwana rwekuti iwe uri boka rine njodzi yechirwere cheshuga.Kuongororwa kwechirwere cheshuga kunotarisa "glycosylated hemoglobin” muropa uye “albumin” muweti.Kana nhamba mbiri idzi dzakakwirira kudarika dzenguva dzose, zvinoreva kuti unogona kunge uchirwara nechirwere cheshuga.Isu tinopa chirongwa cheDiabetes kuti chibatsire mukudzivirira, kuongororwa uye kurapwa kwechirwere cheshuga.Kubva pakuziva zviratidzo zve pre-diabetes kusvika pakurapa chirwere cheshuga retinopathy uye gestational chirwere cheshuga, tinogona kupa kurapwa kwakakodzera uye dzidzo yevarwere vane chirwere cheshuga, kuitira kuti varwere vadzokere kuhupenyu hwese sezvavanokwanisa.
Aehealth InsulinRapid Quantitative Test inoshandisa immunofluorescence.Yakasanganiswa neAehealth Lamuno Ximmunofluorescence kuongororwa, inogona kushandiswa kubatsira mukutaipa chirwere cheshuga uye kuongororwa, kuitira kupa mushonga wakakodzera.
Kurumidza Kuedza: 5-15 min kuwana mhinduro;
Kutakura kwekushisa kwekamuri uye kuchengetedza;
Zvakavimbika Mibairo: Inopindirana kune yepasi rose mwero.
https://www.aehealthgroup.com/immunoassay-system/
Nguva yekutumira: Nov-16-2022